Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243468 (US9427440, 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243470 (US9427440, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243456 (US9427440, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 4.40 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243456 (US9427440, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 4.40 | n/a | 0.0000900 | 2.00E+4 | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243481 (US9427440, 38) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 7.70 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243480 (US9427440, 28) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 9 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243477 (US9427440, 25) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 11 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243469 (US9427440, 17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 18 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243479 (US9427440, 27) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 400 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein [2420-3010] (Hepatitis C virus genotype 1b (isolate Con1) (HCV)) | BDBM243476 (US9427440, 24) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 760 | n/a | n/a | n/a | 7.4 | 25 |
Janssen Sciences Ireland UC US Patent | Assay Description All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us... | US Patent US9427440 (2016) BindingDB Entry DOI: 10.7270/Q2DN43Z6 | |||||||||||
More data for this Ligand-Target Pair |